Rational Design of Self-Emulsifying Pellet Formulation of Thymol: Technology Development Guided by Molecular-Level Structure Characterization and Ex Vivo Testing

J. Macku, K. Kubova, M. Urbanova, J. Muselik, A. Franc, G. Koutna, M. Pavelkova, D. Vetchy, J. Masek, E. Maskova, J. Brus, 2022: Pharmaceutics.

Controlled synthesis of gemini surfactant-capped gold nanoparticles. Gemini structure-nanoparticle properties relationship study

T. Bílik , J. Vysloužil, M. Naiserová, J. Muselík, M. Pavelková, J. Mašek, D. Čopová, M. Čulen, K. Kubová, 2022: Pharmaceutics.

Cytokine expression by CD163+ monocytes in healthy and Actinobacillus pleuropneumoniae-infected pigs

R. Jarosova, P. Ondrackova, L. Leva, K. Nedbalcova, M. Vicenova, J. Masek, J. Volf, J. Gebauer, T. Do, R. Guranc, Z. Sladek, J. Domingueze, M. Faldyna, 2022: Research in Veterinary Science.

Exploration of Neusilin ^® US2 as an Acceptable Filler in HPMC Matrix Systems-Comparison of Pharmacopoeial and Dynamic Biorelevant Dissolution Study

T. Bílik , J. Vysloužil, M. Naiserová, J. Muselík, M. Pavelková, J. Mašek, D. Čopová, M. Čulen, K. Kubová, 2022: Pharmaceutics.

Assessment of Antimicrobic, Antivirotic and Cytotoxic Potential of Alginate Beads Cross-Linked by Bivalent Ions for Vaginal Administration

M. Pavelková, J. Vysloužil, K. Kubová, S. Pavloková, D. Molinková, V. Celer, A. Pechová, J. Mašek, D. Vetchý, 2021: Pharmaceutics.

Short-course sublingual immunotherapy by mucoadhesive patch and tolerogenic particle enhanced allergen presentation

P. Sørensen , P. Turánek-Knotigová, J. Mašek, J. Kotouček, F. Hubatka, E. Mašková, P. Kulich, D. Lubasová, M. Raška, K. Leenhouts, J. Turánek , 2021: Clinical & Experimental Allergy.

Ni and TiO ₂ nanoparticles cause adhesion and cytoskeletal changes in human osteoblasts

M. Štefančík, L. Válková, J. Veverková, J. Balvan, T. Vičar, P. Babula, J. Mašek, P. Kulich, M. Pávková Goldbergová, 2021: Environmental Science and Pollution Research.

A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype

M. Hýžďalová, J. Procházková, S. Strapáčová, L. Svržková, O. Vacek, R. Fedr, Z. Andrysík, E. Hrubá, H. Líbalová, J. Kléma, J. Topinka, J. Mašek, K. Souček, J. Vondráček, M. Machala, 2021: Chemosphere.

Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice

M. Kuchař, P. Kosztyu, V. Daniel Lišková, J. Černý, H. Petroková, E. Vróblová, M. Malý, L. Vaňková, M. Křupka, L. Rašková Kafková, P. Turánek Knotigová, J. Dušková, J. Dohnálek, J. Mašek, J. Turánek, M. Raška, P. Malý, 2021: Virulence.

Targeting Human Thrombus by Liposomes Modified with Anti-Fibrin Protein Binders

Petroková H., Mašek J., Kuchař M., Vítečková Wünschová A.,Štikarová J., Bartheldyová E., Kulich P., Hubatka F., Kotouček J., Knotigová P.T., Vohlídalová E., Héžová R., Mašková E., Macaulay S., Dyr J.E., Raška M., Mikulík R., Malý P., Turánek J., 2019. Pharmaceutics 11(12), 642; https://doi.org/10.3390/pharmaceutics11120642.

Proteins mimicking epitope of HIV-1 virus neutralizing antibody induce virus-neutralizing sera in mice

Kosztyu P., Kuchar M, Cerny J., Barkocziova L., Maly M., Petrokova H., Czernekova L., Liskova V., Raskova Kafkova L., Knotigova P., Masek J., Turanek J., Maly P., Raska M., 2019. EBioMedicine 47, 247-256. doi: 10.1016/j.ebiom.2019.07.015.

Application of Advanced Microscopic Methods to Study the Interaction of Carboxylated Fluorescent Nanodiamonds with Membrane Structures in THP-1 Cells: Activation of Inflammasome NLRP3 as the Result of Lysosome Destabilization

Turánek J., Knötigová P.T., Mašek J., Hubatka F., Kulich P., Kotouček J., Šimečková P., Čelechovská H., Koudelka Š., Procházka L., Bartheldyová E., Héžová R., Švadláková T., Vaškovicová N., Skoupý R., Krzyžánek V., Macaulay S., Fekete L., Machala M., Raška M., Kratochvílová I., 2019. Molecular Pharmaceutics, 2019, 168, 3441-3451.

N-oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells

Bartheldyová E., Knötigová P.T., Zachová K., Mašek J., Kulich P., Effenberg R., Zyka D., Hubatka F., Kotouček J., Čelechovská H., Héžová R., Tomečková A., Mašková E., Fojtikova M., Macaulay S., Bystrický P., Paulovičová L., Paulovičová E., Droz L., Ledvina M., Raška M., Turánek J., 2019. Carbohydrate Polymers 207, 521-532.

Hyaluronic Acid Surface Modified Liposomes Prepared via Orthogonal Aminoxy Coupling: Synthesis of Nontoxic Aminoxylipids Based on Symmetrically α-Branched Fatty Acids, Preparation of Liposomes by Microfluidic Mixing, and Targeting to Cancer Cells Expressing CD44

Bartheldyová E., Effenberg R., Mašek J., Procházka L., Knötigová P.T,, Kulich P., Hubatka F., Velínská K., Zelníčková J., Zouharová D., Fojtíková M., Hrebík D., Plevka P., Mikulík R., Miller A.D., Macaulay S., Zyka D., Drož L., Raška M., Ledvina M., Turánek J., 2018. Bioconjug Chem 29(7), 2343-2356.
doi:10.1021/acs.bioconjchem.8b00311.

Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo

Effenberg R., Knotigova P.T., Zyka D., Celechovska H., Masek J., Bartheldyova E., Hubatka F., Koudelka S., Lukac R., Kovalova A., Saman D., Krupka M., Barkocziova L., Kosztyu P., Sebela M., Droz L., Hucko M., Kanasova M., Miller A.D., Raska M., Ledvina M., Turanek J. 2017. Journal of Medicinal Chemistry 60, 7745-7763.

Multi-layered nanofibrous mucoadhesive films for buccal and sublingual administration of drug-delivery and vaccination nanoparticles – important step towards effective mucosal vaccines

Mašek J., Lubasová D., Lukáč R., Turánek-Knotigová P., Kulich P., Plocková J.,
Mašková E., Procházka L., Koudelka Š., Sasithorn N., Gombos J., Bartheldyová E., Hubatka F., Raška M., Miller A.D., Turánek J., 2017. J Control Release 249, 183–195.

The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice

Krupka M., Masek J., Barkocziova L., Knotigova P.T., Kulich P., Plockova J., Lukac R., Bartheldyova E., Koudelka S., Chaloupkova R., Sebela M., Zyka D., Droz L., Effenberg R, Ledvina M, Miller AD, Turanek J, Raska M., 2016. Plos One 11, Article Number: e0148497.

Molecular Adjuvants Based on Nonpyrogenic Lipophilic Derivatives ofnorAbuMDP/GMDP Formulated in Nanoliposomes: Stimulation of Innate and Adaptive Immunity

Knotigova P.T., Zyka D., Masek J., Kovalova A., Krupka M., Bartheldyova E., Kulich P., Koudelka S., Lukac R., Kauerova Z., Vacek A., Horynova M.S., Kozubik A., Miller A.D., Fekete L., Kratochvilova I., Jezek J., Ledvina M., Raska M., Turanek J., 2015. Pharmaceutical Research 32, 1186-1199.

Enhancement of immune response towards non-lipidized Borrelia burgdorferi recombinant OspC antigen by binding onto the surface of metallochelating nanoliposomes with entrapped lipophilic derivatives of norAbuMDP

Krupka M., Masek J., Bartheldyova E., Knotigova P.T., Plockova J., Korvasova Z., Skrabalova M., Koudelka S., Kulich P., Zachova K., Czernekova L., Strouhal O., Horynova M., Sebela M., Miller A.D., Ledvina M., Raska M., Turanek J., 2012. J Control Release 160, 374-381.

Metallochelating liposomes with associated lipophilised norAbuMDP as biocompatible platform for construction of vaccines with recombinant His-tagged antigens: Preparation, structural study and immune response towards rHsp90

Masek J., Bartheldyova E., Turanek-Knotigova P., Skrabalova M., Korvasova Z., Plockova J., Koudelka S., Skodova P., Kulich P., Krupka M., Zachova K., Czernekova L., Horynova M., Kratochvilova I., Miller A.D., Zyka D., Michalek J., Vrbkova J., Sebela M., Ledvina M., Raska M., Turanek J., 2011. J Control Release 151, 193-201.

Nanofibers in Mucosal Drug and Vaccine Delivery

Mašek J., Mašková E., Lubasová D., Špánek R., Raška M, Turánek J. In: Morari Do Nascimento, G. (Ed.) Nanofibers – from Preparation to Applications. 2019, ISBN 978-953-51-6328-2.

Binding of Polysaccharides onto Liposomes and Characterization of Liposomal Preparation by Physical-Chemical and Advanced Microscopic Methods

Turanek J., Masek J., Raska M., Ledvina M., Paulovicova E., Hubatka F.,
Kotoucek J. In: Maiti, S.: Functional Polysaccharides for Biomedical Application. Elsevier, 2019.

Lipid-Based Nanoparticles and Microbublles

Turanek J., Miller A.D., Kauerová Z., Lukáč R., Masek J., Koudelka S., Raska M. In: Serra, PA: Advances in Bioengeneering. InTech, 2015, ISBN: 978-953-51-2141-1, DOI: 10.5772/59870, 79-116.

Functionalised Nanoliposomes for Construction of Recombinant Vaccines: Lyme Disease as an Example

Turanek J., Masek J., Krupka M., Raska M. 2015. In: Matthias, G: Molecular Vaccines: From Prophylaxis to Therapy, 2019. ISBN 978-3-319-00978-0, DOI: 10.1007/978-3-319-00978-0, 561-577.

Application of Liposomes for Construction of Vaccines

Turanek J., Masek J., Raska M., Ledvina M. In: Ghista, DN: Biomedical Science, Engineering and Technology. InTech, 2011, ISBN: 978-953-307-471-9, DOI: 10.5772/1020, 653-678.