Jan Hošek PhD
IN VITRO AND EX VIVO MODELS
EVALUATION OF NOVEL LOW-MOLECULAR-WEIGHT DRUGS
DEVELOPMENT AND ANALYSIS OF GLUCAN-BASED DRUG VEHICLES
Habilitation in the field of Genomics and Proteomics, Faculty of Science, Masaryk University Brno
Habilitation thesis: “Regulation of the expression and activity of proteins involved in the inflammatory response by natural flavonoids”
Appointed: 1st May 2019, acquired degree: docent (associate professor)
2006 – 2011
Postgraduate study programme at Department of General and Molecular Genetics, Faculty of Science, Masaryk University Brno
Dissertation thesis: “Study of plant compounds with anti-phlogistic effect on the expression of genes connected with inflammatory reaction”
Final state examination: 20th January 2011, acquired degree: Ph.D.
Advanced state examination at Department of General and Molecular Genetics, Faculty of Science, Masaryk University Brno
Advanced thesis: “Single-nucleotide polymorphismus associated to chronic inflammatory bowel disease”
Final state examination: 10th December 2008, acquired degree: RNDr.
Master study programme Department of Genetic and Molecular Biology, Faculty of Science, Masaryk University Brno
Master thesis: “Preparing of PCR internal standards for detection and differentiation of Mycobacterium avium strains”
Final state examination: 20th June 2006, acquired degree: Mgr.
Bachelor study programme at Department of Genetic and Molecular Biology, Faculty of Science, Masaryk University Brno
Bachelor thesis: “Detection of veterinary important mycobacteria in clinical samples”
Final state examination: 24th June 2004, acquired degree: Bc.
Pisárčik M., Lukáč M., Jampílek J., Pašková Ľ., Bilka F., Bilková F., Devínsky F., Vaľko J., Horáková R., Hošek J., Březina M., Opravil T. 2022. Controlled synthesis of gemini surfactant-capped gold nanoparticles. Gemini structure-nanoparticle properties relationship study. Journal of Molecular Liquids. 365: 120210.
Treml J., Šalamúnová P., Hanuš J., Hošek J. 2021. The effect of curcumin encapsulation into yeast glucan particles on antioxidant enzymes expression in vitro. Food & Function.12: 1954-1957.
Cerulli A., Napolitano A., Hošek J., Masullo M., Pizza C., Piacente S. 2021. Antioxidant and In Vitro Preliminary Anti‐Inflammatory Activity of Castanea sativa (Italian Cultivar “Marrone di Roccadaspide” PGI) Burs, Leaves and Chestnuts Extracts and their Metabolite Profiles by LC‐ESI/LTQOrbitrap/MS/MS. Antioxidants. 10: 278.
Magar P., Parravicini O., Štěpánková Š., Svrčková K., Garro A.D., Jendrzejewska I., Pauk K., Hošek J., Jampílek J., Enriz, R.D., Imramovský A. 2021. Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE. Int. J. Mol. Sci. 22: 9447.