Eliška Mašková PhD
Researcher
Research activities
CONTROLLED RELEASE DOSAGE FORMS
MUCOADHESIVE ORAL DOSAGE FORMS
NANOFIBROUS MUCOADHESIVE FILMS FOR ORAL ADMINISTRATION OF DRUGS AND VACCINES
EXCIPIENTS FOR MUCOADHESIVE DOSAGE FORMS
TOPICAL DOSAGE FORM AND TRANSDERMAL DRUG DELIVERY SYSTEMS
NANOTECHNOLOGY BASED DOSAGE FORMS
Project involvement
FIT (Pharmacology, Immunotherapy, nanoToxicology)
OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – Reg.No. CZ.02.1.01/0.0/0.0/15_003/0000495
CEREBIT (Centre for Recombinant Biotechnologies and Immunotherapeutics)
OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – Reg.No. CZ.02.1.01/0.0/0.0/16_025/0007397
IMMUNOPHARMACOTHERAPY
OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – Reg.No. CZ.02.2.69/0.0/0.0/16_018/0002665
IMMUNOPHARMACOTHERAPY – infrastructure upgrade
OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – CZ.02.1.01/0.0/0.0/16_017/0002632
NV16-30299A - Nanoliposomal systems for rapid diagnosis of thrombi by MRI
AZV ČR – NV16-30299A
Education
2012–2014, 2017–2019
Ph.D. in Pharmacy, Pharmaceutical Technology and Galenic Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic
Dissertation thesis: “ Hypromellose in controlled release dosage forms for oral and oromucosal application”
2009
Advanced Master´s degree (Doctor of Pharmacy – PharmD.) in Pharmacy, Pharmaceutical Technology and Galenic Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic
Advanced Master´s thesis: “Determination of ciclopiroxolamine effective concetration for oral mucoadhesive tablets”
2001–2006
Master´s degree (Mgr.) in Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic
Awards
1st place in the “Discovery award” 2017
in the field of mucoadhesive nanofibre-based carriers for non-invasive administration of vaccines and therapeutic nanoparticles (“Mucoadhesive nanofibrous carrier of vaccines and therapeutic nanoparticles”)
1st place in the poster section of the 5th Nano Today Conference 2017
„Sublingual delivery of therapeutic nanoparticles by means of multilayered nanofibre-based mucoadhesive film”, Hawaii, USA, 2017
Dean’s Award
for excellent results presented in diploma thesis, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic, 2006
Selected publications
Rational Design of Self-Emulsifying Pellet Formulation of Thymol: Technology Development Guided by Molecular-Level Structure Characterization and Ex Vivo Testing
J. Macku, K. Kubova, M. Urbanova, J. Muselik, A. Franc, G. Koutna, M. Pavelkova, D. Vetchy, J. Masek, E. Maskova, J. Brus, 2022: Pharmaceutics.
Short-course sublingual immunotherapy by mucoadhesive patch and tolerogenic particle enhanced allergen presentation
P. Sørensen , P. Turánek-Knotigová, J. Mašek, J. Kotouček, F. Hubatka, E. Mašková, P. Kulich, D. Lubasová, M. Raška, K. Leenhouts, J. Turánek , 2021: Clinical & Experimental Allergy.
Hypromellose – a traditional pharmaceutical excipient with modern applications in oral and oromucosal drug delivery
Mašková E., Kubová K., Raimi-Abraham B.T., Vllasaliu D., Vohlídalová E., Turánek J., Mašek J., 2020: Journal of Controlled Release.
Nanofibers in Mucosal Drug and Vaccine Delivery
Mašek J., Mašková E., Lubasová D., Špánek R., Raška M, Turánek J. In: Morari Do Nascimento, G. (Ed.) Nanofibers – from Preparation to Applications. 2019, ISBN 978-953-51-6328-2.
Multi-layered nanofibrous mucoadhesive films for buccal and sublingual administration of drug-delivery and vaccination nanoparticles – important step towards effective mucosal vaccines
Mašek J., Lubasová D., Lukáč R., Turánek-Knotigová P., Kulich P., Plocková J.,
Mašková E., Procházka L., Koudelka Š., Sasithorn N., Gombos J., Bartheldyová E., Hubatka F., Raška M., Miller A.D., Turánek J., 2017. J Control Release 249, 183–195.
Highly soluble drugs directly granulated by water dispersions of insoluble Eudragit® polymers as a part of hypromellose K100M matrix systems
Mašková E., Naiserová M., Kubová K., Mašek J., Pavloková S., Urbanová M., Brus J., Vysloužil J., Vetchý D., 2019. Biomed Res Int. 8043415, doi: 10.1155/2019/8043415.
Modulace uvolňování léčiv z moderních perorálních a orálních hydrofilních matricových systémů na bázi hypromelosy
Mašková E., Kubová K., Mašek J., 2019. Chem. Listy 113, 491–499.
N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells
Bartheldyová E., Turánek Knotigová P., Zachová K., Mašek J., Kulich P., Effenberg R., Zykad D., Hubatka F., Kotouček J., Čelechovská H., Héžová R., Tomečková A.,
Mašková E., Fojtíková M., Macaulaye S., Bystrický P., Paulovičová L., Paulovičová E., Drožd L., Ledvinac M.,Raška M., Turánek J., 2019. Carbohydrate Polymers 207, 521–532.
Influence of pH Modulation on Dynamic Behavior of Gel Layer and Release of Weakly Basic Drug from HPMC/Wax Matrices, Controlled by Acidic Modifiers Evaluated by Multivariate Data Analysis
Mašková E., Kubová K., Vysloužil J., Pavloková S, Vetchý D., 2017. AAPS PharmSciTech 18(4), 1242-1253.