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Mašková Eliška

PharmDr. Eliška Mašková, Ph.D.

researcher

Research activities

CONTROLLED RELEASE DOSAGE FORMS

MUCOADHESIVE ORAL DOSAGE FORMS

NANOFIBROUS MUCOADHESIVE FILMS FOR ORAL ADMINISTRATION OF DRUGS AND VACCINES

EXCIPIENTS FOR MUCOADHESIVE DOSAGE FORMS

TOPICAL DOSAGE FORM AND TRANSDERMAL DRUG DELIVERY SYSTEMS

NANOTECHNOLOGY BASED DOSAGE FORMS

Project involvement

FIT (Pharmacology, Immunotherapy, nanoToxicology)

OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – Reg.No. CZ.02.1.01/0.0/0.0/15_003/0000495

CEREBIT (Centre for Recombinant Biotechnologies and Immunotherapeutics)

OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – Reg.No. CZ.02.1.01/0.0/0.0/16_025/0007397

IMMUNOPHARMACOTHERAPY

OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – Reg.No. CZ.02.2.69/0.0/0.0/16_018/0002665

IMMUNOPHARMACOTHERAPY – infrastructure upgrade

OP RDE project of the Ministry of Education, Youth and Sports of the Czech Republic – CZ.02.1.01/0.0/0.0/16_017/0002632

Education

2012–2014, 2017–2019

Ph.D. in Pharmacy, Pharmaceutical Technology and Galenic Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic

Dissertation thesis: “ Hypromellose in controlled release dosage forms for oral and oromucosal application”

2009

Advanced Master´s degree (Doctor of Pharmacy – PharmD.) in Pharmacy, Pharmaceutical Technology and Galenic Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic

Advanced Master´s thesis: Determination of ciclopiroxolamine effective concetration for oral mucoadhesive tablets

2001–2006

Master´s degree (Mgr.) in Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic

Awards

1st place in the “Discovery award” 2017

in the field of mucoadhesive nanofibre-based carriers for non-invasive administration of vaccines and therapeutic nanoparticles (“Mucoadhesive nanofibrous carrier of vaccines and therapeutic nanoparticles”)

1st place in the poster section of the 5th Nano Today Conference 2017

„Sublingual delivery of therapeutic nanoparticles by means of multilayered nanofibre-based mucoadhesive film”, Hawaii, USA, 2017

Dean’s Award

for excellent results presented in diploma thesis, University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic, 2006

Selected publications

Nanofibers in Mucosal Drug and Vaccine Delivery

Mašek J., Mašková E., Lubasová D., Špánek R., Raška M, Turánek J. In: Morari Do Nascimento, G. (Ed.) Nanofibers – from Preparation to Applications. 2019, ISBN 978-953-51-6328-2.

Multi-layered nanofibrous mucoadhesive films for buccal and sublingual administration of drug-delivery and vaccination nanoparticles – important step towards effective mucosal vaccines

Mašek J., Lubasová D., Lukáč R., Turánek-Knotigová P., Kulich P., Plocková J.,
Mašková E., Procházka L., Koudelka Š., Sasithorn N., Gombos J., Bartheldyová E., Hubatka F., Raška M., Miller A.D., Turánek J., 2017. J Control Release 249, 183–195.

Highly soluble drugs directly granulated by water dispersions of insoluble Eudragit® polymers as a part of hypromellose K100M matrix systems

Mašková E., Naiserová M., Kubová K., Mašek J., Pavloková S., Urbanová M., Brus J., Vysloužil J., Vetchý D., 2019. Biomed Res Int. 8043415, doi: 10.1155/2019/8043415.

Modulace uvolňování léčiv z moderních perorálních a orálních hydrofilních matricových systémů na bázi hypromelosy

Mašková E., Kubová K., Mašek J., 2019. Chem. Listy 113, 491–499.

N-Oxy lipid-based click chemistry  for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells

Bartheldyová E., Turánek Knotigová P., Zachová K., Mašek J., Kulich P., Effenberg R., Zykad D., Hubatka F., Kotouček J., Čelechovská H., Héžová R., Tomečková A.,
Mašková E., Fojtíková M., Macaulaye S., Bystrický P., Paulovičová L., Paulovičová E., Drožd L., Ledvinac M.,Raška M., Turánek J., 2019. Carbohydrate Polymers 207, 521–532.

Influence of pH Modulation on Dynamic Behavior of Gel Layer and Release of Weakly Basic Drug from HPMC/Wax Matrices, Controlled by Acidic Modifiers Evaluated by Multivariate Data Analysis

Mašková E., Kubová K., Vysloužil J., Pavloková S, Vetchý D., 2017. AAPS PharmSciTech 18(4), 1242-1253.