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In vivo imaging laboratory

In vivo imaging laboratory

To observe and characterize patho-morphologic changes, distribution of active compounds and pathogens in organisms, we use noninvasive whole-body imaging techniques, including X-ray microtomography, in vivo fluorescence and bioluminescence. Small-animal whole-body in vivo imaging allows us to simultaneously monitor continuous biological processes in the same animal and can also reduce the number of animals for experimentation. Thus, it is in agreement with 3R principles. We use both mice and rat models in our lab. In addition, imaging modalities can serve for some ex-vivo and in-vitro studies.

Equipment

  • Bruker Skyscan 1276 for x-ray microtomography
  • Bruker Xtreme II system for whole-body in vivo fluorescence and bioluminescence
  • Inhalation anesthesia
  • Stereotactic manipulator

Current research topics

  • Stroke research in rodent models
  • magnetic nanorobots
  • Development of novel contrast agents for microCT
  • Imaging of viral infections in vivo

Head of the laboratory

Cooperation offer

We offer whole-body in-vivo/ ex-vivo imaging in rodent models – tracking and distribution of labeled active compounds or immune cells in organism cancer models

Our partners