The Bruker JPK NanoWizard 4 BioScience is an extreme-performance atomic force microscope for biological applications. It is mounted on a Leica fluorescent microscope and is for AFM routines such as 3D visualization as well as physical evaluation of measured samples. It combines fast tip scanning with high-resolution scan sizes of up to 100 µm2. The architecture of the instrument provides measurements in liquids in heated Petri dishes while observing the sample (f.e. cells) in real time and by using an optical overlay. The microscope is enclosed in an acoustic box and mounted on an active anti-vibration stage.

It is integrated with a Cytosurge FluidFM for single-cell adhesion and injection, spotting, nano-printing, colloidal force spectroscopy, and more.

The whole system can be combined with an Optical tweezer in our lab for unique advanced experiments.